It may take 8 to 12 minutes to reach Al-Mathaf Hotel and Cultural House starting from the middle of Gaza city:

4.8 KM from the UNRWA HQ in Al-Remal Area, to go to Al-Mathaf go West on Jamal Abed El-Nasser St. until you reach Al-Rasheed st., go North all the way through Al-Shatee Refugees Camp, keep going on the Beach road, continue for 200 meters after Arc Med Hotel.
3.5 KM from UNDP building, go North on Azz Addeen Al-Qassam st. (also known as Al-Shifa st.) to the end then take left heading to West until you reach Al-Rasheed st. (Beach road) then go right heading North for 200 meters.
13 KM from Erez Check Point and 45 KM from Rafah crossing.